A significant increase from baseline in Compact disc3+/perforin+?cytotoxic T cells occurred just in the 700-mg imgatuzumab group (median 95% increase, antibody-dependent cell-mediated cytotoxicity (ADCC) and excellent preclinical anti-tumor efficacy with higher infiltration of ADCC-mediating immune system cells into xenograft tumors versus cetuximab [1]
A significant increase from baseline in Compact disc3+/perforin+?cytotoxic T cells occurred just in the 700-mg imgatuzumab group (median 95% increase, antibody-dependent cell-mediated cytotoxicity (ADCC) and excellent preclinical anti-tumor efficacy with…