Thus, from these studies has appeared a functional link between IL-7, IL-7R, and SOCS1 in the regulation and homeostasis of Th17/Th1/Treg cells of relevance to autoimmunity, which seems to be vindicated by the identification of hard-wired polymorphisms in the 3 corresponding gene loci that act as susceptibility factors for MS (Zuvich and others2010; Vandenbroeck and others2011)
Thus, from these studies has appeared a functional link between IL-7, IL-7R, and SOCS1 in the regulation and homeostasis of Th17/Th1/Treg cells of relevance to autoimmunity, which seems to be…