Significantly, B-1 B cell responses bring about clonal enrichment of cells inside the self-renewing B cell pool, that display characteristics of immunological memory, including robust clonal proliferation and rapid antibody-secreting cell differentiation upon secondary antigen exposure (98,99,102,103) (JSN and RGK, unpublished observations)
Significantly, B-1 B cell responses bring about clonal enrichment of cells inside the self-renewing B cell pool, that display characteristics of immunological memory, including robust clonal proliferation and rapid antibody-secreting…